After successfully penetrating the blood brain barrier, Vinpocetine is able to rapidly exert its action within neuronal tissue by allowing more oxygenated blood to access the brain and improve cognitive processes.Most notable benefits occur to the visual cortex, thalamus and basal ganglia.
Many neurodegenerative disorders have been linked to an increase in cerebral inflammation which has been implicated in both Parkinson’s and Alzheimer’s. This is the reason why Vinpocetine has found some promising research with studies looking into treatments for these conditions, as the anti-inflammatory effects could help diminish the symptoms for sufferers.
A technique called Sternberg which is used by scientists to assess the memory of volunteers was used during research into Vinpocetines cognitive benefits, and concluded that a single dose of just 40mg caused a statistically significant memory increases, as well as further improvements to reaction speeds when compared to a placebo. Another study has found that in 12 healthy volunteers, the administration of Vinpocetine also increased their memory capacity.
Further findings in healthy female subjects has found that the reactions speeds were increased after Vinpocetine was taken.
How does Vinpocetine work?
Many of the neuroprotective properties of Vinpocetine have been attributed to its action as a channel blocker. Specifically the Na (Sodium) channel and as an inhibitor to phosphodiesterase. By preventing the up-regulation of NF-kB, Vinpocetine is able to prevent neuroinflamation.