Extensive research has deduced that Phenibut is extremely effective at reducing anxiety, fear and stress seen in many situations,  with further cognitive benefits attributed to its ability to improve the sleep patterns and REM duration. Phenibut has been recognized in the Russian federation as a primary tool for those working through their juvenile years in space travel, as this period is met with high levels of stress and fear. It was concluded that Phenibut would be chosen for cosmonauts as it did not cause the sedation and cognitive impairment of other tested tranquilizers.
There have been a wide variety of studies conducted using Phenibut, with some common disorders. Both psychosomatic and neuronic patients experiencing fear, stress and tension have found some relief with Phenibut use, expanding to those with post-traumatic stress also.
Further studies, mainly in Russia, have found statistically significant reduction in the induced amnesia caused by scopolamine intoxication. Anti-oxidant effects shown in the spleen have been noted in one piece of research.Further studies have tested the effects Phenibut can have on those suffering from alcohol intoxication which can cause severe brain damage. Not only was Phenibut able to protect from this brain damage but was also found to prevent is during oxygen starvation.
How does Phenibut work?
The action of Phenibut is mainly due to its ability to bind to both the GABA B and the GABA A receptor. Here, it acts as a potent agonist causing these inhibitory effects which give it such a useful therapeutic profile. At higher does it seems to bind more at the GABA A receptor. This action reduced the tension in the body and can inhibit even some of the norepinephrine release in the hippocampus, which can help to diminish the stimulation caused by anxiety and other excitatory nootropics. Phenibut can also act on some of the reward neurotransmitters within the brain which has been linked to its ability to reduce anxiety and alleviate the symptoms of low mood.