Choline plays a pivotal role in the brains ability to produce acetylcholine. Memory, attention, focus and learning are all affected by the abundance of acetylcholine within the brain. 1975 was the year science discovered how important choline is to our brains, and since this time it has become the focus of thousands of research programs. When we wake in the morning our immediate sensory perception is key to feeling alert, and acetylcholine is able to help us feel more revitalized as it involved in this first tactile response.
The benefits of Citicoline are mainly seen as a result of a larger reservoir of “fuel” for other nootropics to work with. Almost all nootropics work via a mechanism which will require high levels of acetylcholine within the brain, and without this, the cognitive benefits are simply not as strong. This can be particularly obvious when some nootropic users experience mild headaches as a result of insufficient choline levels, as their brains have used up all of the available choline. This can be reduced and stopped by immediate intake of a good source of choline such as Alpha GPC, Citicoline or Centrophenoxine.
After years of studies into the effectiveness of Citicoline the following benefits have been found:
- Clear boosts in learning and memory in various studies using animals.
- Implicated in healthy pregnancies as choline plays such a vital role in a mothers early maternal phases, as such, lower incidences of birth complications have been found when Citicoline was administered.
- Those with low mood, Bipolar, Alzheimer’s and vision defects have all seen health benefits relating to Citicoline supplementation.
- Further studies have indicated a strong action as a psychostimulant and a neuroprotective agent.
How Does Citicoline Work?
An important protein known as phosphatidylcholine is the key enzyme responsible for converting choline into the useful neurotransmitter acetylcholine. More of this key enzyme can allow for a higher rate and eventual level of available acetylcholine. Due to the fact that Citicoline can raise levels of this enzyme it is no wonder that it has such a vast array of cognitive benefits owing to acetylcholine.
Citicoline can act as a psychostimulant via its action on the prefrontal lobe and also by maintaining the function of the somatic nervous system. Its action as a CNS stimulant is key to the strong benefits seen in maintaining focus and attention, while the neuromodulating properties may owe to its beneficial effects on neuronal plasticity and the structure of cell membranes.