500mg Aniracetam


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Aniracetam UK

 

Overview

Aniracetam (AkA Draganon, Sarpul, Ampamet, Memodrin or Referan) is a nootropic racetam supplement with up to ten times more potency than the first racetam produced. Aniracetam, as an AMPA receptor modulator, is able to boost memory and improve judgment while also stimulating the brain for an enhanced attention span, learning process and level of alertness.[4][5] Aniracetam has also been found to be useful for treating the symptoms of memory loss and depression in Alzheimer’s disease and dementia.[3][6][7][8] Aniracetam has shown effective against certain anxiety related disorders and social failure/impairment.[1] Further studies suggest a neuroprotective action exceeding those seen by the first racetam.[6]

 

Key Findings

Potential shown against anxiety-related disorders and social failure/impairment.[1]

Facilitates learning, attention span and alertness.[2][5][10]

Shown to increase levels of reward and empathogen neurotransmitters.[8]

Shown to enhance memory in healthy people.[4]

Shown to alleviate symptoms of dementia.[3]

Shown alleviate symptoms of depression.[3][7][6]

High neuroprotective potential.[3][6][9]

 

Details

Aniracetam shares much of the same cognitive profile as the other major members of the Racetam family such as Pramiracetam, Oxiracetam, Phenylpiracetam and Nefiracetam. Aniracetam is an Ampakine nootropic Racetam and benefits from a wide therapeutic safety profile with almost no side effects. Research into Aniracetam has shown a neuroprotective action after cholinergic antagonists, cerebral ischaemia, electroconvulsive shock and scopolamine induced brain damage. Aniracetam is able to protect neuronal cell death to a greater extent than previous racetams.[1][9] 

Based on its action upon reward, empathogen and the AMPA receptor, studies have found it to alleviate symptoms of anxiety disorders, social failure/impairment and phobias, as well as reduce depression.[1][7][11] As an Ampakine it has a profound effect upon those suffering from Alzheimer’s disease and various cognitive impairments as the potential to reverse the effects of such ailments is recognised, as well as the potential to protect neurones before brain damage can occur. AMPA receptor modulation, glutamate and BDNF actions allow Aniracetam to improve attention, learning and memory, while also increasing neuronal plasticity.[3][4][10]  

Aniracetam shares many of the common racetam nootropic actions; as such you may find some cited sources pointing to studies on other racetams.

 

How Does Aniracetam Work?

Aniracetam is able to have a positive effect on memory, attention and learning via its action upon neuronal plasticity and AMPA receptor modulation. Via the release of Glutamate Aniracetam is able to facilitate fast synaptic transmission within the central nervous system.[10][2][5]

A positive action upon mood is seen after the use of Aniracetam, and its ability to help those with anxiety is mediated through its reward systems, empathogen and cholinergic action. Reward signalling via the nicotinic acetylcholinergic receptors may also be a mechanism of action for alleviated depression and anxiety.[3][6][8][7]

Aniracetam is able to bind allosterically to the AMPA receptor; changing the binding site and modulating the effects of bound neurotransmitters such as acetylcholine and glutamate. This allosteric binding also allows the receptor to benefit from a reduced rate of desensitization.[12]

Based on the way that most racetam nootropics work, it is extremely safe to take Aniracetam even at high doses. There are no serious side effects and it is virtually non-toxic. Long term use is extremely beneficial due to its neuroprotective action.

 

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Aniracetam - Cited Sources

[1] http://www.ncbi.nlm.nih.gov/pubmed/11412837

[2] http://www.ncbi.nlm.nih.gov/pmc/articles/PMC53047/

[3] http://www.ncbi.nlm.nih.gov/pubmed/22070796

[4] http://www.ncbi.nlm.nih.gov/pubmed/826948

[5] http://www.ncbi.nlm.nih.gov/pubmed/17119538

[6] http://www.ncbi.nlm.nih.gov/pubmed/8199398

[7] http://www.ncbi.nlm.nih.gov/pubmed/11959085

[8] http://www.ncbi.nlm.nih.gov/pubmed/11597608

[9] http://www.ncbi.nlm.nih.gov/pubmed/6817363

[10] http://www.ncbi.nlm.nih.gov/pubmed/10627576

[11] http://www.ncbi.nlm.nih.gov/pubmed/11702095

[12] http://www.ncbi.nlm.nih.gov/pubmed/1660156

 

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