Sunifiram review: Benefits, mechanism of action, dosage and safety

09/05/2015 Tags: all

Please note: This article is for informational purposes only. We do not endorse intake or use of unifiram or any other nootropic substances listed on this blog. Any adverse events associated with the use of this substance are sole responsibility of the user.

One of the newest nootropic substances being sold in the market nowadays includes sunifiram. Sunifiram is one of the lesser known and relatively new nootropic agents  that has shown promising results. It is categorized as an ampakine nootropic supplement primarily because of its function as an AMPA agonist. Reviews from users liken its mechanism to that of piracetam albeit it is considered to be a thousand times more potent than piracetam. Sunifiram is a very potent substance effective in improving memory function, attention span, alertness, learning and decision making abilities. Subjective reports from users reveal that it is one of the most popular nootropic agent that could help students in improving their concentration.

What is sunifiram?

Despite the raving reviews about this new nootropic substance, what exactly is sunifiram?

Well, sunifiram is a relatively new nootropic agent that has been researched in 2000. It has similar chemical structure to piracetam although initial studies have shown that it is substantially more powerful than this popular racetamig substance. So far, sunifiram has shown exceptional positive results as a memory enhancer. Currently, it is being subjected to in depth investigations for its potential ability to treat cognitive diseases such as Alzheimer’s disease.

Reviews about sunifiram shows that this nootropic supplement greatly helps in improving information recall whilst promote clarity of thoughts. In terms of potency, sunifiram has been compared with noopept. Early observations and comparisons revel that noopept is more effective in promoting alertness and focus while sunifiram is identified to be more potent in boosting memory.

What are the benefits of sunifiram supplementation?

Sunifiram is thought to work similarly with other racetamic agents. It is able to stimulate many of the receptors influenced by most racetams, albeit in different ways. The primary effect of sunifiram supplementation has been associated with AMPA receptors stimulation (hence identified as an ampakine nootropic agent). Studies have shown that sunifiram is able to increase the activity of AMPA receptors. Note that AMPA receptors play a critical role in the production of glutamate in the brain.

Glutamate is a very important brain chemical as it is responsible for various activities within the brain. Some of its activities include creating connections between synapses, regulating neuronal survival as well as signaling excitatory transmissions. This neurotransmitter is also involved in synaptic plasticity and brain metabolism. Low levels of glutamate in brain will negatively affect cognitive abilities resulting to poor learning abilities, difficulty remembering information and decreased attention span. Sunifiram is able to reverse these unwanted side effects through increasing glutamate levels in the brain thereby enhancing its performance in the long run. It also helps in making information recall and new concept learning a lot easier even during long periods of heightened mental exertion.

Similar to pramiracetam, oxiracetam, aniracetam, piracetam and most nootropic agents, sunifiram improves acetylcholine levels in the brain. It serves as an cholinergic which therefore increases release of acetylcholine neurotransmitters in the brain. Note that increased levels of acetylcholine in specific parts of the brain helps in enhancing memory, focus, alertness, perception, thinking and concentration. Acetylcholine also makes it easier for your right and left brain hemispheres to communicate which aides in improving your ability to recognize connections and patterns and social skills.

Other benefits associated with sunifiram intake is increased stimulation. Subjective reports from users identified sunifiram to produce a stimulation effect that is similar to taking Adderall. Fortunately, despite having similar effects when it comes to stimulation, sunifiram does not causes negative side effects (e.g. anxiety, irritation, high blood pressure, irregular heartbeat). Sunifiram is also though to help in increasing one’s ability to concentrate as well as enhance energy levels. Moreover, sunifiram helps increase motivation and productivity through eliminating procrastination in doing school and work tasks. Anecdotal evidence further shows that it can help in promoting weight loss and is an effective pre-workout supplement amongst others.

How much sunifiram should you take?

Please always bear in mind that sunifiram is a highly concentrated nootropic agents. You will be able to notice beneficial effects even after taking a dosage that is as little as 4 mgs. 5 to 8 mgs of sunifiram taken at a time can already help in exerting most of its beneficial effects. Going beyond this range, say taking a 10 mg dose could already cause a stimulant effect similar to that of Adderall. Although a 10 mg dose is considered as non-toxic, it might cause serious unwanted side effects such as increased perspiration and body temperature. Due to these unwarranted side effects, we recommend that you stay within the suggested dosage and start taking sunifiram at 3 mgs for your first week. Only increase your sunifiram dosage intake once your body gets used to it.