Phenylpiracetam for Mental and Physical Enhancement

27/05/2014 Tags: all, sport

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First developed in Russia in the early 1980s, Phenylpiracetam is among the more potent and advanced supplements from the racetam family. This nootropic is essentially a phenylated version of the first developed nootropic from the racetam class, Piracetam. Yet despite relatively small structural differences, Phenylpiracetam is thought to be up to 60 times as potent as its predecessor. Not only does it improve cognitive performance to a greater degree than Piracetam, but Phenylpiracetam also offers additional benefits as a physical performance enhancing supplement; Phenylpiracetam is actually known to increase physical stamina as well as tolerance to both mental and physical stress. With all these benefits to mind and body it is no wonder that Phenylpiracetam is becoming increasingly more popular and available in the west. If you want to increase your ability to focus, learn and remember information, or need a supplement to improve your exercise routine Phenylpiracetam could be great supplement to add to your regimen. However, before using this supplement it is a good idea to learn a little about its benefits, mechanisms, potential side effects and usage guidelines, all of which will be covered in this article.

 

What are the Benefits of Phenylpiracetam?

‚ÄčOwing to the fact that Phenylpiracetam and Piracetam have similar molecular structures, these supplements share a number of effects, particularly in regard to Phenylpiracetam’s ability to enhance cognition. Users are likely to experience improvements to memory performance, with a greater ability to both form and recall information. Learning capacity which is linked to memory is also likely to see improvements, while users may also benefit from increased levels of focus and concentration, making this nootropic just as useful in the classroom as it is out on the sports field.

Phenylpiracetam is also believed to work in a therapeutic capacity as well as enhancing cognition in healthy individuals. Research from a handful of small scale clinical studies has demonstrated an improvement in a number of encephalopathic conditions which include traumatic brain injury, lesions in blood pathways of the brain, and tumours that originate in the brain or spine (glioma). Other experimental evidence using animal models shows that this supplement is more effective than Piracetam in restoring cerebral blood flow following arterial occlusion.

Additionally, this supplement appears to have mood modulating properties. Through altering the levels of various transmitters that include NDMA, GABA, acetylcholine and dopamine, this supplement is able to reduce stress and anxiety. This trait can be useful in helping to calm pre-test nerves or in reducing mental and physical stress.

 

As mentioned earlier, Phenylpiracetam also appears to be a potent physical performance enhancer. One major benefit that this supplement offers is to increase the body’s resistance to environmental stress. Individuals using Phenylpiracetam for physical performance often report that they find it easier to cope with even intense workout sessions. These stress resistance properties also extend to other areas with the ability to increase the user’s tolerance to cold climatic conditions, a property which can be useful for athletes training all year round.  Athletes using this supplement also report an increase in endurance and stamina with improved recovery time. This supplement is so effective as a cold resistance and stamina enhancing supplement that it has actually been banned by the World Anti-doping Agency and you may remember the disqualification of Russian silver medallist Olga Pyleva during the 2006 Winter Olympics after the use of Phenylpiracetam. However, this ban does not mean that Phenylpiracetam is dangerous in any way, but simply attests to its efficacy as a performance enhancer that gives its users a definite advantage.

Phenylpiracetam may also be useful as an alertness promoting agent. It appears to have stimulatory effects on the central nervous system that can aid users in feeling more awake after periods of sleep deprivation. Reports suggest that this supplement can improve the clarity of thoughts while making you less susceptible to mental fatigue. The rush of energy experienced when using Phenylpiracetam has led to many individuals using this nootropic as an alternative to Modafinil and other stimulants. These properties of Phenylpiracetam make it a very useful supplement for shift workers and those with irregular work or sleep schedules alike.

 

How Does Phenylpiracetam Work?

Although Phenylpiracetam is very similar to Piracetam, the additional phenyl structure of this molecule means it has a higher bioavailability and absorption rate. As a result, relatively small amounts of Phenylpiracetam are required to achieve the same effect seen with large amounts of Piracetam. The underlying mechanisms however are not too dissimilar.

Though the mechanisms of racetams are not fully understood, there are a few generally accepted theories of how they work. Phenylpiracetam appears to modulate the action of several key neurotransmitters. For example, many of its cognition enhancing benefits can be partly attributed to increases in acetylcholine activity. This neurotransmitter is vital in the processes of learning and memory while increased acetylcholine receptor density in the hippocampal regions of the brain has also been linked to the generation of new neurons, and subsequent increases in synaptic plasticity.

Phenylpiracetam like many other racetams is classed as an ampakine with the ability to affect AMPA receptors that correspond to glutamate. This action is thought to be responsible for some of the attention and focus enhancing benefits of this supplement, as well further improving upon learning and memory performance. Ampakines have a distinct advantage over other stimulants like caffeine and Ritalin in that they do not generally cause long-lasting negative side effects such as fatigue and sleepiness.

 

 

Phenylpiracetam is also classed a dopaminergic supplement meaning it modulates the activity of dopamine systems and this is achieved through increasing the number of dopamine receptors. Dopamine is linked to mood and movement, among other functions, which may explain this supplements effectiveness as a motion sickness aid, as well as some of the mood modulating effects it has. The stress and anxiety relieving properties of this supplement however are more likely to be attributable to the action it has on gamma-aminobutyric acid (GABA). This neurotransmitter is the chief inhibitory neurotransmitter found in the brain that generally has a calming effect. This can be useful in pacifying excessive stimulatory signals in the brain that are characteristic of anxious states of mind.

 

Recommended Dosage

Due to the fact that this supplement is relatively potent, users are advised to begin with the lowest effective dosage of Phenylpiracetam. Some users notice effects with dosages as small as 100mg, although typical dosages range up to 300mg. As Phenylpiracetam has a half-life span of around 5 hours, this dosage should be divided into 2 or 3 equally sized administrations to be taken throughout the day in order to ensure a consistent level of effects. Due to this supplements stimulant like effects, you should avoid using this supplement late in the day as it may result in difficulty sleeping.

It is important to note that there is the potential to develop a tolerance to Phenylpiracetam making it less effective than previously. To avoid this, Phenylpiracetam should only be used occasionally, perhaps for a few days a week before taking a week or two off. Alternatively it can be used as needed, for example before an important meeting, exam, or sporting competition when physical or mental performance needs to be at its peak.

Potential Side Effects

Much like the other nootropic supplements, Phenylpiracetam is generally considered to be safe and well tolerated. It does not appear to exhibit any drug interactions, although certain individuals including nursing and pregnant women should not use this supplement due to a lack of research on side effects in these groups. Furthermore, Phenylpiracetam is not physiologically addictive although there are some reports of psychological addiction. It should be noted that in most instances, this has only occurred at dosages far in excess of the recommended level.

A majority of side effects seen with Phenylpiracetam are common to other racetam supplements. These side effects are usually quite rare and mild in nature and may include headaches, irritability, nausea and gastrointestinal distress. The most common of these are headaches, most likely caused by increased acetylcholine activity creating a greater demand for choline (the precursor of acetylcholine). Headaches can be easily overcome by taking an additional choline supplement like Citicoline or Centrophenoxine. Other side effects may be remedied by reducing your dosage, or discontinuing use for a while until symptoms no longer persist.