Novel uses of Ipamorelin

09/06/2015 Tags: all

Please note: This article is for informational use only. We do not encourage intake of Ipamorelin or any other peptides/nootropics listed on this site. Any undesirable effects from use of Ipamorelin are sole responsibility of the user.

What is ipamorelin?

Ipamorelin is a synthetic peptide known to have excellent abilities in the release of growth hormones like GHRP-6. It is characterized by five amino compoundss and a fairly short chain. Because of this, it has the ability to increase the rate of muscle growth and loss of fat at the same time.

As a pentapeptide, ipamorelin is considered to have milder effects as compared to the hexapeptide, hexarelin. Still, it has the ability to mimic the ability of natural growth hormones. Today, we will be providing a brief overview about ipamorelin and focus on its novel uses.

What are the benefits of ipamorelin use?

Promotes muscle growth without causing cartilage or bone deformity

One of the most interesting findings on studies done with the administration of ipamorelin includes its ability to promote muscle growth and development. Several studies have shown that it is able to help increase muscle mass and tissues without causing bone development or increase on any bone development serum markers. For instance, the amount of cells found in the shin bone have not changed significantly even with prolonged administration of ipamorelin. This is a good thing since it suggests that it does not cause cartilage or bone deformities.

Acts as a selective growth hormone releaser

Aside from promoting muscle growth, some studies have discovered that plasma growth hormone levels are substantially reduced and unchanged (most of the time) even after the administration of increased amounts of GHRH). This finding is actually advantageous as it only shows that ipamorelin does not influence the natural growth hormone production of your body. This demonstrates the fact that this peptide is a selective growth hormone releaser. More importantly, ipamorelin is able to similarly and effectively release growth hormones alongside the celebrated GHRP-6.

Does not cause hunger issues

Unlike hexarelin or GHRP-6, researchers discovered that ipamorelin does not cause hunger making it advantageous for individuals who are under a restricted calorie diet. Note however that there may be aggravation of ipamorelin’s side effects when used in conjunction with anabolic steroids since these substances also influence the production of insulin growth factor (IGF) and growth hormone.

Releases growth hormones comparable with GHRP-6

Another astounding characteristic of ipamorelin include its ability to release growth hormones similar to what GHRP-6 can do. What makes it unique however is the fact that it has not affected serum plasma levels of TSH, PRL, LH or FSH in the blood.

Does not cause increases in cortisol and acetylcholine levels

In theory, it has been thought that ipamorelin may increase the levels of cortisol and acetylcholine when used in much higher doses similar to what GHFRP-6 and GHRP-2 can do. Studies however revealed that there was little to no increase in cortisol and acetylcholine levels in the blood even when the study subjects were given 200 times more than the identified effective dosage for growth hormone release. This only proves that ipamorelin is a successful GHRP receptor agonist 0 a chemical that is able to bind with a cell receptor to trigger a specific and selective response for the increased release of growth hormone.

Novel uses of ipamorelin

Increase bone mineral content

In an animal study using rats as the study subjects, ipamorelin is thought to help in improving bone mineral content. Earlier, it has been clearly stated that ipamorelin does not cause any bone or cartilage deformity. Somehow however, some researchers have discovered conflicting results. In the aforementioned study, the rats were given ipamorelin for 12 weeks. Anatomic study of the research subjects revealed that it is only able to increase the cortical BMC in the cross section of the bone area.

Treat postoperative ileus

Some other studies claimed that ipamorelin is also able to help in treating symptoms of postoperative ileus amongst rodents. After administration of 2 doses of ipamorelin per day for a period of time, it was revealed that the peptide is able to decrease the length of the first bowel movement – still, it has not produced any untoward effects to food intake, fecal output or in the body weught.

Despite this, you must always bear in mind that administration of repeated dose of ipamorelin can influence food intake, pullet output and body weight gain. This shows that administering ipamorelin in postsurgical settings could easily help decrease symptoms of individuals suffering from POI.

Proper ipamorelin dosage

Recommended dosage for ipamorelin is 200 mcg to 300 mcg daily. Some suggests that you take it after a heavy workout or 30 to 45 minutes before.

Is ipamorelin safe to use?

Generally, ipamorelin is safe to use. Nonetheless, prospective users must exercise precaution in using it. Before purchasing ipamorelin, you must know how to use it appropriately