Nootropics: A healthy way to promote brain health and fight ageing

06/01/2015 Tags: all

Please note: We do not encourage intake of any nootropic agents. Use of these compounds is not for human consumption. Nootropics are intended for research purposes only. Adverse effects and complications of these drugs due to abuse and unwarranted intake are sole responsibility of the user.

When people think about staying healthy and fit, most focus from the neck to down. Less attention was given on the important role played by the brain on most of our daily activities. Well, you must know that every second of the day, your brain is continuously working and aging at the same time and that a healthy brain is foremost in maintaining important activities such as remembering, focusing, feeling, working, thinking, sleeping, and even feeling!

While we age, different toxins (e.g. lipofuscin) accumulate in the brain cells. The neurons will become less responsive while losing their fluidity. Numerous environmental factors such as excessive alcohol intake, smoking, unhealthy diet and other unhealthy activities lead to oxidative stress all of which contributes to premature neuronal apoptosis or cell death.

Similar to most parts of your body, your brain will eventually lose its agility as you grow older. Evidence of brain deterioration however may be harder to see. As such, it is critical that you take several steps to reverse and slow down brain aging. One popular strategy to slow down brain deterioration includes ingestion of brain supplements. Such supplements are known as nootropics. Nootropics are drugs that enhance brain health, improve cognitive performance and increase memory capacity.

As research on nootropics expand, many are currently being studied as treatments for several cognitive problems associated with aging and other disorders such as Alzheimer’s disease and Parkinson’s disease. Nootropic combinations are now being used to improve cognitive health and delay the commencement of age related problems of the brain. Some nootropics actually functions to form synapses and neurons that improve intellect and cognitive performance overtime. To help you in choosing the right nootropic supplements, we have provided a list below. The best nootropic drugs that can help in maintaining a healthy brain as it ages are discussed.


The aging brain and nootropic supplementation


Free radical damage

Free radicals are molecules that are disengaged from their parent compounds. These molecules damage cells and even cause certain types of cancer. Free radical formation is induced by oxidative stress that increases in our brain as we age. If left unrestrained, free radicals will eventually cause cognitive deterioration through interfering with the activities of your neurons. Antioxidants reduce free radicals. As such, it is critical that you add antioxidants on your daily health regimen. Fortunately, many nootropic agents such as melatonin, ginkgo biloba, ginseng, ashwagandha and some racetams functions as antioxidant that helps in decreasing the levels of free radicals in the brain.


Decreasing brain plasticity

Your brain has the ability to adapt and alter/modify itself when exposed to new environment, learning and settings. This ability is known as brain plasticity whereas it continuously rewires itself as you gain knowledge and experiences, form and store memories and learn. This is how the brain creates, weakens, strengthens and destroys neuronal connections formed from our memories. However, as the brain ages, this ability is diminished – this is also the primary reason why it is harder for elderlies to learn new things.

Through proper supplementation and exercise, we can help our aging brain to develop new neuronal connections. Neuronal plasticity can be increased through supplementing with powerful and potent nootropic agents such as noopept, piracetam, oxiracetam, aniracetam and pramiracetam. These agents help in increasing the acitivities of acetylcholine in the brain. Moreover, noopept helps in increasing Nerve Growth Factor that regulates the growth of neurons and neurites.


Chemical changes

As we age, our gray matter declines. Degradation of this brain component is problematic as it plays a critical role in the brain’s chemical composition. Aging also causes the decrease in the levels of neurotransmitter. Neurotransmitters are chemical messengers of our brain cells. These are being utilized by the brain to perform most of our though and memory functions.

 Important neurotransmitters including acetylcholine, dopamine, serotonin and glutamate decrease as we age. Dopamine is responsible to motor activities and moods. Serotonin on the other hand helps regulate learning, sleep, mood and memory while glutamate prevents the occurrence of neurological conditions such as Alzheimer’s. Acetylcholine plays a critical role with all memory processes – collection, formation, encoding, recall and consolidation.

To help fight back against these undesirable chemical changes, a number of nootropic drugs can supplement and promote healthy gray matter whilst promote increased levels of neurotransmitters. These nootropic drugs include Huperzine A, vinpocetine, aniracetam, piracetam, choline, centrophenoxine and alpha GPC. Stacking or combining these nootropic drugs to some other nootropics will potentiate its effects on the brain.


Toxin accumulation

The accumulation of toxins in the brain is another concern that occurs as we age. One problematic toxin that accumulates in the body and in the brain is lipofuscin. Lipofuscin or liver spots are detectable on the skin of elderly individual. It might surprise you to know that even your brain develops these spots due to lipofuscin.

It is critical that lipofuscin is immediately and properly removed from the brain. Lipofuscin can actually deter cell maintenance processes resulting to neuronal premature death. One nootropic agent known to decrease lipofuscin build-up on the brain and skin includes Centrophenoxine.

In taking these supplements, we suggest that you first consult your doctor.