Hexarelin: The less understood growth hormone

07/06/2015 Tags: all

Please note: This article is for informational use only. We do not encourage intake of Hexarelin or any other peptides/nootropics listed on this site. Any undesirable effects from use of Hexarelin are sole responsibility of the user.

Hexarelin is a peptide with six amino compoundss attached to its chemical structure similar to GHRP-6. However, one can say that hexarelin is so unlike other GHRP’s available today. Many consider hexarelin as an underdog. It is one of the many substances that have not received attention because it is thought to lack some important qualities that excellent peptides must have. Suffice to say that hexarelin is a peptide that has been highly underestimated. Today however, we will tell you why this specific peptide must not be pushed aside, but rather, evaluated and assessed to deeply understand its benefits amongst athletes and bodybuilders.

Hexarelin background

You must know that hexarelin is not your typical GHRP. Its structure as a hexapeptide makes it an excellent channel to promoting the increased release of growth hormones. Although its mode of action has not been fully understood by experts, it is well known that it acts on both the hypothalamic area and pituitary gland. More importantly, it is the one peptide that is able to produce the largest amounts of growth hormones.

Similar to most peptides, hexarelin is able to increase the release of natural growth hormones. More importantly, it does not decrease the natural ability of the body to release growth hormones. Several studies have also shown that it increases fat loss, strengthen connective tissues, improve elasticity of the skin and increase mitosis, meiosis and bone mineral density.

What are the benefits of hexarelin use?

As aforementioned, hexarelin produces the greatest pulse amongst other GHRP. It increases lean body mass (LBM) through acting on the hypothalamus and pituitary gland. It greatly helps in fat reduction whilst helps in increasing bone mineral density as shown in some animal studies. Moreover, it has anti-aging properties wherein it is able to help heal or improve the ageing skin.

What makes hexarelin unique however includes its cardioprotective properties. Studies have discovered that it has the ability to act on most cardiac receptors aside from its growth hormone releasing properties. It can directly help protect the heart from problems caused by left ventricular pressure issues whilst help in healing heart scar tissues. Animal studies using laboratory rats also revealed that both lean and obese rats are able to receive cardioprotective properties from the administration of hexarelin.

How does hexarelin works?

The exact mechanism of action of hexarelin is yet to be identified. Studies however have shown that once hexarelin is injected via the subcutaneous route, it activates the functioning of the pituitary gland through a pulse. Similar to GHRP-6, it helps improve the circulation of growth hormones within the body. Despite having similarities with GHRP-6, it acts differently in some ways. For one thing, it does not cause any hunger issues. It is true that hexarelin is able to increase growth hormones level in the body however, it is also able to decreases somatostatin – one of the main causes of non-production of growth hormones. This means that there will be increased levels of growth hormones. Moreover, as the most potent available GHRP, users should always bear in mind that desensitization with hexarelin is much quicker as compared to other GHRP’s. Hence, hexarelin is not ideal for long term use. Note however that with its ability to raise IGF-1 and growth hormone levels, it can work as an excellent PCT tools for individuals who are cycling off with synthetic IGF-1 or other growth hormones. It is also best that users must never underestimate its potency particularly in increasing levels of prolactin and cortisol. It has the strongest affinity to increasing cortisol and prolactin compared to other available GHRP’s.

Is it safe to use?

Hexarelin is relatively safe to use when administered as recommended by manufacturers. 200 mcg daily dose of hexarelin is purported to be sufficient in producing the desired effects. However, users and prospective users must know that it causes several undesirable effects including lowered libido, difficulty in maintaining relations because of increased prolactin levels, increased cortisol and prolactin levels and gynecomastia.

Buy hexarelin vial

Hexarelin is available as a free dried powder similar to other synthetic growth hormones. Unreconstituted hexarelin must be stored in a cool dry place. Reconstituted hexarelin vials on the other hand must be placed in a refrigerator.


Hexarelin is available in vials as a freeze dried powder. Sterile water is needed to dilute the powder and an insulin syringe is the preferred syringe in administering the diluted hexarelin via the subcutaneous route. Users must always remember not to use hexarelin for a long period of time as it can cause desensitization.