Centrophenoxine review: Benefits, dosage, side effects and stacking

09/03/2015 Tags: all

Please note: This article is for informational purposes only. We do not encourage intake of centrophenoxine or any nootropic agents. Any undesirable effects from intake of this nootropic substance are sole responsibility of the user.

Despite being the lesser understood nootropic supplement, centrophenoxine is a very powerful neuro enhancing nootropic substance available in the market today. It has been studied by researchers for the past five decades; hence, it is only apt to say that it is an effective smart drug safe for human use. Centrophenoxine is also known to enhance cognitive performance particularly in the areas of focus, concentration, alertness, attention, learning and memory. A number of studies have also shown that it can help in boosting brain health through improving cellular function and decreasing the rate of neuronal aging. It also helps in promoting improved neuronal performance by eliminating the toxic wastes (lipofuscin and potassium) that naturally accumulates in your neurons. More importantly, it is known to be an excellent source of acetylcholine. In this guide, we will be discussing about the benefits, dosage, side effects and stacking of centrophenoxine.

What is centrophenoxine?

Centrophenoxine, also known by its trade names – Lucidril and Meclofenoxate, is a well-known nootropic agent that has some potent effects in decreasing the rate of aging amongst its users. It is a compound of parachlorophenoxyacetate and dimethyaminoethanol (DMAE). In many ways however, it is considered to be more potent than its parent compound, DMAE. Being the enhanced version of DMAE, centrophenoxine is able to exert the beneficial effects of the said cognitive enhancing agent in addition to its anti-aging properties.

What are the benefits of centrophenoxine supplementation?

In a cognitive standpoint, studies and anecdotal evidence have shown that centrophenoxine supplementation can help in improving attention, focus, and learning capacity. It is also known to influence any memory processes including memory recall, formation, retention and conversion of short term memory to long term memory.

Studies have also shown to positively influence Alzheimer’s disease, dementia and other age related memory decline/deterioration. It is known to improve memory loss amongst both healthy and elderly individuals who are supplementing with centrophenoxine. It significantly helps in improving memory recall and in converting recent information/data to long term memory.

Individuals suffering from dementia symptoms also report positive effects after supplementing wit meclofenoxate. Some studies give evidence on its efficiency to slow down rate of age related memory decline through enhancing intracellular water content and in increasing cell division. Centrophenoxine is thought to increase the rate of cell division through preventing the accumulation of potassium and lipofuscin in the neuronal cells which leads to the decreased rate of cellular aging.

What are the possible side effects of centrophenoxine supplementation?

Many studies have shown that centrophenoxine has low toxicity to humans. It has been proven to be relatively safe for human use. However, since it is a potent neuro enhancing agent, some users may experience mild undesirable effects such as irritability, headaches, nervousness, fatigue, nausea, difficulty sleeping and gastrointestinal issues (e.g. diarrhea). At much higher doses, centrophenoxine may lead to jaw clamping. If these rare effects occur, it is suggested that you discontinue centrophenoxine use for a few days until these symptoms are resolved or lower your dose at recommended levels.

How should you use centrophenoxine?

The recommended daily dose for centrophenoxine is 500 to 1000 mgs. It is suggested that younger individuals take 250 to 500 mgs a day while elderly individuals take 750 to 1000 mgs a day for optimal results. We recommend however that you stay within this range to prevent the abovementioned side effects.

You may opt to take centrophenoxine once a day or split your target dose to 2 – 3 divided doses. It is highly recommended that you take it in the morning or not later than midday as it is known to increase your energy which may keep you awake at night. However, if you wish to work at night or pull an all nighters, then you may take centrophenoxine later in the afternoon.

Lactating and pregnant mothers should not take centrophenoxine. If you are suffering from any medical condition or is taking any other supplements or medications, we recommend that you consult your doctor before using centrophenoxine. Unknown drug to drug interactions may occur if centrophenoxine is used with other medications, drugs, or supplements.

Centrophenoxine stacking

Centrophenoxine’s potential beneficial effects are increased when stacked with other nootropic agents. Some nootropic substances that may help potentiate centrophenoxine’s effect include racetams and acetyl L-carnitine. This particular nootropic agent is best stacked with piracetam not only because it works synergistically. Piracetam signals the brain to produce more acetylcholine while centrophenoxine makes it probable for your brain to produce more acetylcholine. Note that centrophenoxine is an excellent source of choline – a precursor of acetylcholine. Therefore, centrophenoxine and piracetam stack is recommended if you want to potentiate both nootropic supplements’ beneficial effects to your body.